# NIH Human-Based Research Toolkit: Unlocking Predictive Power, Reducing Costs, and Accelerating Translation

## ‍ **Overview**

The NIH’s groundbreaking shift to prioritize human-relevant science marks a paradigm change for biomedical research institutions. This toolkit outlines how VeriSIM Life’s BIOiSIM® platform enables researchers to align with NIH’s new direction, **replacing traditional animal testing with predictive, clinically relevant AI-driven tools**. For institutions, this shift doesn’t just improve science—it enhances funding competitiveness, reduces R&D costs, and accelerates translational impact.

## **Why It Matters for Institutions:**

**Increased NIH Funding Eligibility**: Align with priority areas for new NIH grant opportunities focused on human-based research.

**Lower Preclinical Costs**: Reduce or eliminate animal studies, which often represent 30–50% of early-stage R&D budgets.

**Faster Time to IND**: BIOiSIM® de-risks candidates earlier, cutting 6–12 months from development timelines.

**Higher Translational Success Rates:** Replace low-predictive animal models with human-relevant simulations, increasing clinical success probability.

## **Reputation & Partnership Readiness:**

Join a forward-looking ecosystem of AI-powered translational research and attract academic-industry collaborations.

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